Order Crystallization Screens: JBScreen Cryo
Cryocooling crystals reduces radiation damage rates, and is often essential to obtaining a complete X-ray data set. Cryomethods allow crystallographers to work with smaller crystals, and cryocooled crystals can be stored indefinitely without losing diffraction quality. However, crystals can be damaged by ice formation during cooling.
Cryoprotectants provide a means to inhibit ice formation and protect macromolecular crystals from damage during the cryocooling process.
JBScreen Cryo is an advanced screen for cryo conditions. The four JBScreen Cryo kits contain the 96 most successful crystallization conditions found to be suitable for cryo crystallography. As with the JBScreen Classic system, the formulations of JBScreen Cryo were determined by extensive data mining.
JBScreen Cryo is available in the standard 10 ml bulk format or in pre-filled 96-well deep well plates - JBScreen Cryo HTS.
JBScreen Cryo can be used in standard vapor diffusion setups to determine conditions suitable for cryo crystallography "from scratch", or to find a suitable cryo condition when crystals are grown with a standard (non-cryo) screen.
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How the JBScreen buffers are prepared
More information: JBScreen Cryo User Guide