MicroRT X-Ray Capillary Aligner for Diffraction Screening:
Find out why your crystals don't diffract at cryo temperatures. Our new MicroRT Capillary Aligner makes high-throughput room-temperature diffraction screening a breeze. Mount your crystal and loop in one of our goniometer bases, attach to a standard magnetic wand, and place on the right side of the aligner. Inject your reservoir solution into a MicroRT capillary, and place on the left side. Then use the aligner to precisely guide the capillary past your crystal and onto the base. Go from a crystal in a drop to a crystal in the X-ray beam in two minutes. A big hit at the ACA and ICCBM meetings.
Reusable Goniometer Bases (Caps):
No more gluing loops into bases, or fumbling for a base with the right loop size. Our patent-pending designs grab and securely hold MicroMounts, MicroLoops and all other standard crystal loops without epoxy, glue or grease. Simply insert the mount's rod into the base, and then push down using our heavy-duty tweezers until the grip is secure. Survey your plates for crystals, and then quickly assemble mount + base combinations to match the harvesting and data collection challenges they present.
Magnetic CryoVials™ and Assemblies:
We now offer SPINE-standard magnetic CryoVials, as well as mount, base and vial assemblies. We use a translucent polymer with excellent dimensional stability on cooling and a ring magnet that releases from the base/cap before the cryovial releases from SPINE automounter magnets, so as to ensure reliable automated handling. Compatible with all automounters that use vials, all vial handling hardware and all standard bases/caps. Order them alone, with goniometer bases, or as vial, base and mount/loop assemblies.
Protein Crystallography Starter Kit™:
Mitegen's Protein Crystallography Starter Kit has everything you need to mount and collect X-ray data from your crystals at both room temperature and at cryo temperatures. Each kit contains 20 MicroMounts, 3 reusable goniometer bases, 3 magnetic CryoVials, 20 MicroRT Capillaries, 1 pair heavy-duty tweezers and a 24 page instruction manual. A great training tool for new students and technicians. Contact us for quantity discounts for workshops and summer schools.
We now offer MRC 2-well and 3-well 96 well plates and hanging drop plate seals from Swissci at very competitive prices. Superb optics, easy crystal harvesting, UV transparency and exceptional plate flatness have made these plates the number one sellers in Europe.
Can't get your protein to crystallize? The JBS Floppy Choppy Kit provides a clever and convenient approach to protein modification through limited proteolysis. Just add the premixed protease solutions to your protein solution immediately prior to crystallization. No need to stop the proteolysis or purify the fragments: the magic of crystallization will automatically select out crystallizable fragments as they form.
Phosphotungstate Clusters for MIR and MAD Phasing:
In addition to the powerful Tantalum Cluster and Magic Triangle, we now offer a Phosphotungstate Cluster Kit for MIR and MAD phasing. Tungsten is a strong anomalous scatterer, and this 12 tungsten cluster has high electron density and very good solubility in aqueous solutions.
The perfect tweezers for handling MicroMounts, MicroLoops, MicroMeshes, and MicroGrippers. Heavy duty serrated tips firmly grip the stainless steel pins without slipping. Ideal for inserting pins/loops into our reusable goniometer bases.
The world's most advanced loop design, MicroLoops LD have earned a large following since their introduction in late 2009. They provide a nearly ideal combination of low drop disturbance, excellent rigidity and low background X-ray scatter. Puncture right through your protein skin and retrieve your crystal without perturbing the rest of the drop. The tool of choice for harvesting crystals from sub-microliter drops and from microfluidic cards.
MicroLoops E™ have elongated apertures for retrieving needle or rod-shaped samples. Small fingers projecting into the aperture gently support your sample, and allow each aperture to be used with a wider range of sample sizes. Choose between horizontal, vertical or inclined apertures. Horizontal aperture loops can be used to gently scrape samples off the bottom of a well. Inclined apertures improve crystal orientation for more efficient data collection.
