JBScreen pH-2D allows sampling of a broad pH range without changing the buffering environment . This ensures that pH screening is independent of the chemical nature of the components of the buffer system.
JBScreen pH-2D contains six extended range buffer systems, each composed of a mixture of three individual buffers with a distinct chemical nature and well separated pKa values. Each buffer system is composed of a low-pH and a high-pH stock solution, supplied in 10 ml volumes. The low-pH stock solution is preset at pH 4.0 and the high-pH solution at either pH 9.0 or 10.0 (see download). Thus, mixtures of the low-pH and high-pH stock solutions in different proportions provide coverage of the entire pH range from 4.0 – 9.0 or 4.0 – 10.0, respectively. The composition of the buffer systems assures a virtually linear distribution of the resulting pH vs the percentage of high pH / low pH stock.
Larger volumes are available upon request. Newman (2004) Novel buffer systems for macromolecular crystallization. Acta Cryst. D60:610.
Note: This is a special order item with 2-4 weeks delivery , during our initial phase of carrying Jena products. If you would like us to stock this item, please let us know!