The practical crystallization course is in fact the 9th run of the FEBS practical courses “Advanced methods in macromolecular crystallization“, organized since 2004. The planned course (for undergraduate, postgraduate students and postdocs with an interest in macromolecular crystallization) is rather different from the established courses in protein crystallization. The course is designed to bring over the message of the benefits of more rational approaches to macromolecular crystallization and is aimed at a healthy mixture of advanced theoretical discussions and laboratory experiments. To achieve this goal, we have invited a number of prominent experts in the field as a teachers and tutors.