- Reduce evaporative losses
- Aid in drop placement
- Increase crystal size and quality
DropSaver™ Lid for MiTeGen's In-Situ-1 plate
Custom designs available
Reduce evaporation during filling
Even with a robot, chances are that your first drops are evaporating measurably before your last drop is set and your plate is sealed.
DropSaver™lids protect your protein drops from ambient air motion that leads to rapid evaporation during the plate loading process
as high as 90% reduction in evaporation rates when using DropSaver™ Lids
Aid in consistent drop placement
Consistent and easy drop setting, especially valuable to when hand displacers are used
Increase crystal size and quality
Using lids proved to produce larger and better diffracting crystal for some protiens.
Custom DropSaver™ Lids for use with ADE systems (Accoustic Drop Ejection)
Special high-tolerance DropSaver™ Lids are excellent for protecting the nano-sized drops used in ADE populated experiments
In combination with custom DropSaver™ Lids, ADE devices can be used to populate plates with ultra-small protien droplets, up to 1728 per plate! 
6 drops per well (576 drops per plate), dispensed via ADE
18 drops per well(1728 drops per plate),dispensed through slits in a custom DropSaver™ Lid, via ADE2
for MiTeGen In-Situ-1 Plates (4 lids)
Precision DropSaver™ lids for MiTeGen's In-Situ-01 plates
for ARI 3-well low-profile INTELLI-PLATE
Precision drop saver lids for Art Robbins 3-Well low-profile INTELLI-PLATE
DropSaver™ bundle other SBS plates (4 lids)
Using a different plate and want the benefits of DropSaver™ Lids?
|DropSaver™ Lids for ADE||contact us|
Can I just 3D print my own lids?
Yes you can. In fact some prototype and early stage DropSaver™ Lids were made using 3D printing techniques. However these provide to be inferior in regards to uniformity, alignment; and most critically, vapor transmission and evaporation rates. For this reason MiTeGen provides DropSaver™ Lids that are micro-machined in low-permeability molded polystyrene.
|Material||Clear Polystyrene (PS)|
For additional questions about other properties of DropSaver™ Lids please call +1 607 266 877 or email email@example.com.
 A simple technique to reduce evaporation of crystallization droplets by using plate lids with apertures for adding liquids L. E. Zipper, X. Aristide, D. P. Bishop, I. Joshi, J. Kharzeev, K. B. Patel, B. M. Santiago, K. Joshi, K. Dorsinvil, R. M. Sweet and A. S. Soares, Acta Crystallographica Section F, Volume 70, part 12, Dec. 2014.
 High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density Ella Teplitsky, Karan Joshi, Daniel L. Ericson, Alexander Scalia, Jeffrey D. Mullen, Robert M. Sweet, Alexei S. Soares, Journal of Structural Biology, July 2014, pp 49-58