Polyhedral (A) and ball and stick (B) representation of [TeW6O24]6− with different coordination modes of the oxygen atoms in panel B. Figure used by courtesy of Prof. Annette Rompel, University of Vienna.Full Description
The Anderson−Evans polyoxotungstate [TeW6O24]6− (TEW) is a universal and flexible additive for protein crystallization. With its planar structure and high negative charge, it has proven to promote crystal contacts, improve crystal quality and further provides a valuable anomalous signal for phasing due to 6 tungsten atoms.
For in vitro use only!
Shipping: shipped at ambient temperature
Storage Conditions: store at ambient temperature
Shelf Life: 12 months
Molecular Formula: Na6[TeW6O24] x 22 H2O
Molecular Weight: 2148,90 g/mol
Solubility: 100 mM in water
Dissolve 1 g Na6[TeW6O24] x 22 H2O in 4,65 ml water to achieve a 100 mM stock solution.
 Bijelic et al. (2017) Ten Good Reasons for the Use of the Tellurium-Centered Anderson-Evans Polyoxotungstate in Protein Crystallography. Acc. Chem. Res.50:1441.
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 Molitor et al. (2016) In situ formation of the first proteinogenically functionalized [TeW6O24O2(Glu)]7- structure reveals unprecedented chemical and geometrical features of the Anderson-type cluster. Chem. Commun. 52:12286.
 Molitor et al. (2015) Crystallization and preliminary crystallographic analysis of latent, active and recombinantly expressed aurone synthase, a polyphenol oxidase, from Coreopsis grandiflora. Acta Cryst. F 71:746.
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