CryoSol
MD1-90 is presented as 33 x 1.5 mL microtubes.
A set of multicomponent solutions intended for ligand solubilisation/soaking of hydrophobic ligands into crystals and subsequent crystal cryoprotection with CryoMixes™. The compositions of the mixes include dioxane, butanediol as well as DMSO. Whilst high DMSO concentrations can be detrimental to proteins, high dioxane concentrations on the other hand, are well tolerated. Dioxane is also effective for ligand solubilization alone and in conjunction with other organic compounds with cryoprotectant properties. This kit is intended for ligand solubilization to prepare protein-ligand complexes for co-crystallization screening. It is also intended for the preparation of ligand-loaded cryosolutions for soaking into crystals.
- Manufacturers SKU: MD1-90
- MiTeGen SKU: M-MD1-90
Product Information
Features of CryoSol:
- Solubilization of hydrophobic ligands.
- Easily prepare ligand-loaded cryosolutions for soaking experiments.
- Co-crystallization screening of protein-ligand complexes.
- Protein friendly mixes of Dimethyl sulfoxide (DMSO/dioxane/ethylene glycol should improve ligand solubilization).
- Contains 2,3-butanediol- compatible with enzymatic activity.
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