2016 CRYSTALLOGRAPHY CATALOG NOW AVAILABLE
LCP crystallization — in meso, in situ serial X–ray crystallography
“This is a truly exciting development. We have demonstrated the method on a variety of cell membrane proteins, some of which act as transporters. It will work with existing equipment at a host of facilities worldwide, and it is very simple to implement.”
— Martin Caffrey
Professor of Membrane Structural and Functional Biology
Follow @MiTeGen on Twitter for more X–ray crystallography links
Image source: Nature A paper published in Nature has revealed the structure of the Rous sarcoma virus’s intasome that is similar to the intasome of HIV and enables inception of the viral genome into the cell. The discovery continues the work of Dr. Duane Grandgenett, PhD who discovered viral integrase in 1978 which led to the creation of effective drugs for HIV management still in use today. Read more to learn about how effective HIV drug treatment regimes are instituted to fight resistance.
Image source: Nature Lytic polysaccharide monooxygenases (LPMOs) break down polysaccharides in a step-wise fashion, and details of the first step of that process has come from discovery of the strucure of LPMOs and polysaccharides in complex with each other.
UNIVERSITY OF ROCHESTER SYMPOSIUM
Biochemistry and Molecular Biology (BMB) Retreat – March 17, 2016
MICROTOOLS STARTER KITS
Get up–and–running with the right tools for your crystals
MiTeGen MicroTools™ help you to measure and manipulate your crystal samples. They are rigid enough for precision yet flexible enough to not harm your crystals.
- (20) Individual MicroTools (Kit #1/2/3) on 25 mm rods, preloaded into reusable magnetic bases
- (1) Magnetic Push-button Wand (for easily switching between tools)
- (1) Serrated-end tweezers
- (1) Holder and case
- (1) Tool location placard
CRYSTALLIZATION IN SPACE
Our In Situ-1 crystallization plates
A set of MiTeGen’s In Situ–1 crystallization plates are blasting off to outer space aboard SpaceX flight CRS-8. The launch is currently scheduled for April 2016.
The plates will be used as part of a microgravity protein crystallization research project being conducted on the International Space Station.
Products from MiTeGen are mentioned hundreds of times a year in scholarly articles
Energy Environ. Sci
Sabrina Beckmann, et al.Web. Print, Protein Amyloid Aggregation (2016)
Armin Wagner, Ramona Duman, Keith Hendersona and Vitaliy MykhaylykWeb, Science Direct, (2016).
If you have solved a structure using MiTeGen products and would like to be featured in our newsletter, drop us a line!
HARVESTING TIPS POSTER
Streamline your crystal harvesting with this collection of tips
How you handle and mount your crystals has a large impact on the quality of the data you can obtain from them. Our new Harvesting Tips poster lays out simple techniques to efficiently harvest all kinds of crystals. It features a clean design, plain language, and visual examples that even undergraduates can understand.