MiTeGen NewsLetter

Crystallography News, Tools & Tips

March 2016


2016 CRYSTALLOGRAPHY CATALOG NOW AVAILABLE

Learn about the latest in plates, screens, mounts and equipment
  • Discover new tools to optimize your work
  • Grow better crystals with the latest screens
  • Collect better data with the leading mounts
  • Receive a set of lab posters too!

Request a free copy!


LCP crystallization — in meso, in situ serial X–ray crystallography

“This is a truly exciting development. We have demonstrated the method on a variety of cell membrane proteins, some of which act as transporters. It will work with existing equipment at a host of facilities worldwide, and it is very simple to implement.”

— Martin Caffrey
Professor of Membrane Structural and Functional Biology

MiTeGen IMISX Plate


CRYSTALLOGRAPHY NEWS

Follow  on Twitter for more X–ray crystallography links
Researchers solve crystal structure of HIV–related intasome


Image source: Nature             A paper published in Nature has revealed the structure of the Rous sarcoma virus’s intasome that is similar to the intasome of HIV and enables inception of the viral genome into the cell. The discovery continues the work of Dr. Duane Grandgenett, PhD who discovered viral integrase in 1978 which led to the creation of effective drugs for HIV management still in use today. Read more to learn about how effective HIV drug treatment regimes are instituted to fight resistance.

Structure solved for step in enzymatic biofuel production


Image source: Nature        Lytic polysaccharide monooxygenases (LPMOs) break down polysaccharides in a step-wise fashion, and details of the first step of that process has come from discovery of the strucure of LPMOs and polysaccharides in complex with each other.


UNIVERSITY OF ROCHESTER SYMPOSIUM

Biochemistry and Molecular Biology (BMB) Retreat – March 17, 2016
MiTeGen was excited to attend the 11th Annual Biochemistry & Molecular Biology Retreat. The retreat was organized by Dr. Clara Kielopf and held at The Historic German House in Rochester, NY. The event provided an exciting venue for our new Sales Manager, Joyce Frank View Joyce Frank's profile on LinkedIn, to begin her introduction to the crystallography community. Joyce brings to MiTeGen experience working with scientists – at the bench, in business development, sponsored research, and intellectual property. She spent 10 years in Sales and Sales Management at Life Technologies while living in Rochester NY. It was a special welcome for her to reconnect with friends and customers while meeting new ones.

MICROTOOLS STARTER KITS

Get up–and–running with the right tools for your crystals

MiTeGen MicroTools™ help you to measure and manipulate your crystal samples. They are rigid enough for precision yet flexible enough to not harm your crystals.

  • (20) Individual MicroTools (Kit #1/2/3) on 25 mm rods, preloaded into reusable magnetic bases
  • (1) Magnetic Push-button Wand (for easily switching between tools)
  • (1) Serrated-end tweezers
  • (1) Holder and case
  • (1) Tool location placard

Buy Now!


CRYSTALLIZATION IN SPACE

Our In Situ-1 crystallization plates

A set of MiTeGen’s In Situ–1 crystallization plates are blasting off to outer space aboard SpaceX flight CRS-8. The launch is currently scheduled for April 2016.

The plates will be used as part of a microgravity protein crystallization research project being conducted on the International Space Station.

Read the Press Release Here!


CITATIONS

Products from MiTeGen are mentioned hundreds of times a year in scholarly articles
Preparation of Crystalline Samples of Amyloid Fibrils and Oligomers

Energy Environ. Sci
Sabrina Beckmann, et al.WebPrintProtein Amyloid Aggregation (2016)

MiTeGen MicroLoops LD™

In–vacuum long–wavelength macromolecular crystallography

Armin Wagner, Ramona Duman, Keith Hendersona and Vitaliy MykhaylykWebScience Direct, (2016).

NVH Oil™

If you have solved a structure using MiTeGen products and would like to be featured in our newsletter, drop us a line!


HARVESTING TIPS POSTER

Streamline your crystal harvesting with this collection of tips

How you handle and mount your crystals has a large impact on the quality of the data you can obtain from them. Our new Harvesting Tips poster lays out simple techniques to efficiently harvest all kinds of crystals. It features a clean design, plain language, and visual examples that even undergraduates can understand.

Request a free copy!

Tip: Mount Size

MicroLoops LD

Tip: Needle Crystal

MicroLoops E

Tip: MicoTools

MicroTools

Request a free copy!